After a chance encounter, a terminally ill ball of sunshine talks a grumpy drifter into driving him across the desert to meet a maybe-real doctor. What should be a quick trip becomes a wild, chaotic, and heartwarming ride that changes them in ways neither saw coming.
Advertising executive Nick Beame learns that his wife is sleeping with his employer. In a state of despair, he encounters a bumbling thief whose attempted carjacking goes awry when Nick takes him on an involuntary joyride. Soon the betrayed businessman and the incompetent crook strike up a partnership and develop a robbery-revenge scheme. But it turns out that some other criminals in the area don't appreciate the competition.
A group of teens hit the road in a stolen driver's ed car, racing against time to help a lovesick high school senior track down his college-freshman girlfriend and win her back.
Xixo is back again. This time, his children accidentally stow away on a fast-moving poachers' truck, unable to get off, and Xixo sets out to rescue them. Along the way, he encounters a couple of soldiers trying to capture each other and a pilot and passenger of a small plane, who are each having a few problems of their own.
Rhode Island State Trooper Charlie Baileygates has a multiple personality disorder. One personality is crazy and aggressive, while the other is more friendly and laid back. Both of these personalities fall in love with the same woman named Irene after Charlie loses his medication.
What should have been a romantic getaway turns into one hilarious debacle after another when Michael's woman dumps him in the desert where he gets carjacked by a teenager and he is taken hostage in a stickup at the local Sip and Zip.