Diego and Gio', inseparable friends, face the battle against the disease that marks Gio's life, always finding a reason to joke. Amid laughter, and moments of deep closeness, they know their bond is facing the most painful farewell.
A poor, struggling South Carolinian mother and daughter face painful choices with their resolve and pride. Bone, the eldest daughter, and Anney her tired mother, grow both closer and farther apart: Anney sees Glen as her last chance.
Jonathan is a young man with a strange condition that only his brother understands. But when he begins to yearn for a different life, their unique bond becomes increasingly tested.