In a post-apocalyptic wasteland where zombies roam, a grizzled mercenary and a young woman must fight their way to a safe haven before they become prey.
Years after a mysterious plague has devastated the planet and turned most of humanity into blood-hungry creatures, a rogue drifter on a vengeful hunt stumbles across a band of survivors in an abandoned police station and reluctantly agrees to try to help them defend themselves and escape to the sanctuary they so desperately need.
Grindhouse combines Robert Rodriguez's Planet Terror, a horror comedy about a group of survivors who battle zombie-like creatures, and Quentin Tarantino's Death Proof, an action thriller about a murderous stuntman who kills young women with modified vehicles. It is presented as a double feature with fictitious exploitation trailers preceding each segment.
When his home of New Eden is destroyed by a revitalized Brotherhood and its new Vamp leader, Martin finds himself alone in the badlands of America with only the distant memory of his mentor and legendary vampire hunter, Mister, to guide him.