94-year-old Eleanor Morgenstein tries to rebuild her life after the death of her best friend. As a result, she moves back to New York City after living in Florida for decades.
Jo, the mother of seven children, divorces her second husband in order to marry Jake, a successful but promiscuous screenwriter. Though they are physically and emotionally compatible, they are slowly torn apart.
Middle-aged widow Beatrice Hunsdorfer and her daughters Ruth and Matilda are struggling to survive in a society they barely understand. Beatrice dreams of opening an elegant tea room but does not have the wherewithal to achieve her lofty goal. Epileptic Ruth is a rebellious adolescent, while shy but highly intelligent and idealistic Matilda seeks solace in her pets and school projects, including one designed to show how small amounts of radium affect marigolds.
An unlikely friendship evolves over one wild night in LA between a struggling journalist and actor Hervé Villechaize, the world's most famous gun-toting dwarf, resulting in life-changing consequences for both.