After returning to Los Angeles from a group therapy session, documentary filmmaker Bob Sanders and his wife, Carol, find themselves becoming vigilante couples counselors, offering unsolicited advice to their best friends, Ted and Alice Henderson. Not wanting to be rude, the Hendersons play along, but some latent sexual tension among the four soon comes bubbling to the surface, and long-buried desires don't stay buried for long.
In post-9/11 New York City, an eclectic group of citizens find their lives entangled, personally, romantically, and sexually, at Shortbus, an underground Brooklyn salon infamous for its blend of art, music, politics, and carnality.
At the house of a famous Chinese botanist teacher his daughter and a female intern fall in love with each other - a forbidden love that must be kept secret.
Brandon, a thirty-something man living in New York, eludes intimacy with women but feeds his deepest desires with a compulsive addiction to sex. When his younger sister temporarily moves into his apartment, stirring up bitter memories of their shared painful past, Brandon's life, like his fragile mind, gets out of control.