In New York City, the lives of a lawyer, an actuary, a house-cleaner, a professor, and the people around them intersect as they ponder order and happiness in the face of life's cold unpredictability.
Paul, a 20 year old midwesterner, arrives at the central bus station and quickly catches eyes with Wye, a 22 year old girl voguing on the sidewalk. After Paul seeks her out in secret, an intense love between them blossoms. But when Paul discovers Wye is trans, he is forced to confront his own identity and what it means to belong.
Pennsylvania, 1993. After getting caught with another girl, teenager Cameron Post is sent to a conversion therapy center run by the strict Dr. Lydia Marsh and her brother, Reverend Rick, whose treatment consists in repenting for feeling “same sex attraction.” Cameron befriends fellow sinners Jane and Adam, thus creating a new family to deal with the surrounding intolerance.
Davey Gordon, a New York City boxer at the end of his career, falls for dancer Gloria Price. However, their budding relationship is interrupted by Gloria's violent boss, Vincent Rapallo, who has eyes for Gloria. The two decide to skip town, but before they can, Vincent and his thugs abduct Gloria, and Davey is forced to search for her among the most squalid corners of the city, with his enemy hiding in the shadows.