In a post-apocalyptic future, the planet is devoured by disease. In order to survive, two brothers can only count on each other. They work as a team until one of them, K, gets seriously injured. R, the youngest, has to make significant decision for both of them.
Due to an experimental vaccine, Dr. Robert Neville is the only human survivor of an apocalyptic war waged with biological weapons. Besides him, only a few hundred deformed, nocturnal people remain; sensitive to light, and homicidally psychotic.
When a U.S. Marine returns home from Afghanistan, he finds that the place he once called home is no better than the battlefields he fought on overseas. Accompanied by his best friend, he searches desperately for the whereabouts of his estranged son and wife. In their search, the two intercept a man carrying vital information about his family.
In a time of starvation, a survivalist lives off a small plot of land hidden deep in forest. When two women seeking food and shelter discover his farm, he finds his existence threatened.