Sara and Enrique's marriage is going through a monotonous crisis he's completely clueless about. Fortunately, Sara hears from Lucy a secret that might be the answer to saving her relationship: Lucy and Ricardo practice polygamy.
Laura has been with Antonio all her life and, just when she begins to wonder if that is really the life she wants, Sergio and Siena cross paths in their lives. Sergio is a former high school classmate and Siena, his millennial girlfriend who arrives to revolutionize everyone's lives. Laura, Raquel and Cris, close friends for years, convince their respective husbands to play a game that Siena proposes to them: the game of keys. The game consists of everyone putting their keys in a bowl. At random, each one chooses some keys and he must go to spend the night with the owner of the keys. This game will revolutionize the group of friends and their lives. It will make them discover who they are and what they really want.
The eldest of the family, Sara, comes of age and brings chaos to the family by announcing her intention to marry Ocho. Javier and Marisa try to avoid it at all costs. At the same time Dani has an existential crisis, Paulita feels jealous of Cris, Carlota announces that she has found a boyfriend from a high society family and Rocio has finally managed to be cast in her first film.
Andrea, a successful veterinarian who loves her job and is in a relationship with Lucio, an up-and-coming lawyer who grew up in the country. Lucio has some news for Andrea: his mother is turning 60 and is throwing a big party to celebrate. Andrea visits the town where Lucio was raised for the first time and would like to become very close to his family, especially her new Mother-in-law Blanca, who is an overprotective mother, ultra-conservative and always thinks she’s right about everything. Andrea tries to fit in by tolerating all her quirks and harsh treatment during the torturous weekend.
A bigamist with one family in Buenos Aires and the other in Mar del Plata sees his life turned upside down when his wives discover what he has hidden from them for so many years and unite to take revenge.