As the world searches for a cure to a devastating virus, a scientist and a park scout venture deep into the woods. As night falls, their journey becomes a terrifying voyage through the heart of darkness as the forest comes to life around them.
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Cocky researcher Sebastian Caine is working on a project to make living creatures invisible. Determined to achieve the ultimate breakthrough, Caine pushes his team to move to the next phase — using himself as the subject. The test is a success, but when the process can't be reversed and Caine seems doomed to future without flesh, he starts to turn increasingly dangerous.
One night, an unusual stranger in need asks a woman living alone in a house in the woods if he can use her phone. It soon becomes clear that they're playing a strange mind game and that there's something very wrong about the woods.
A research scientist explores the boundaries and frontiers of human consciousness. Using sensory deprivation and hallucinogenic mixtures from Native American shamans, he explores these altered states of cognizance and finds that memory, time, and reality itself are states of mind.
Three strangers arrive one by one to a mysterious cabin in the middle of nowhere after enduring separate life-altering predicaments. Searching for a way out of the woods, frustrated, hungry and battling to stay warm they discover their mysterious connection and realize what they have to do in order to get out of the woods alive.
After an experimental drug trial goes awry, the test subjects face a terrifying side effect: if you fall asleep you die. Trapped in an isolated facility, panic ensues as they try to escape and somehow stay awake.