In a dysfunctional family, nobody knows the father's whereabouts, the mother has an affair with a man, son Octavio is going to marry a killer, son Julián claims he had sex with his brother's fiancée, and an illegitimate daughter shows up.
A psychotic man opens fire in a diner, murdering numerous people before killing himself. The survivors struggle in different ways following this horrendous event: a doctor doubts his own instincts and elects to use an experimental medical procedure on his wife, while a gambler believes he's on a lucky streak. A waitress begins engaging in promiscuous sex, and a young girl whose father is among the dead gains unexpected fame.
Rosario Tijeras has been abused by men all her life, initially by her stepfather. Years later, she works as a paid assassin, seducing men and killing them when they least expect it. She meets Emilio, a wealthy womanizer, and his best friend, Antonio, at a nightclub, and starts an affair with Emilio despite Antonio's growing feelings for her. But circumstances bring her closer to Antonio, until her past catches up with her in a devastating way.
Fresh out of prison, Ava's attempt to reclaim her drug operation collapses when she witnesses a brutal crime, forcing her to flee into a nightmarish underworld where allies are scarce and enemies multiply by the minute.
A Marine veteran working as a school janitor tries to mend his relationship with his son after a divorce. When his son is killed by a police officer found innocent without standing trial, he takes matters into his own hands.
Catalina is a young, beautiful girl living in extreme poverty with her brother Bayron and her mother Hilda. She becomes obsessed with getting breast implants to get social status and money. She leaves her boyfriend Albeira and becomes a prostitute for drug dealers. In this way she will enjoy all the luxuries that she lacks. Meanwhile, her ex-boyfriend Albeira and her mother Hilda begin a relationship behind her back.