An immigrant in search of the American dream is forced to take a room in a boarding house and soon finds herself in a nightmare from which she can't escape.
After a family tragedy, Chuck Wilson hopes to start a new life in Ashland Falls with his wife Maria and little sister Elizabeth, but he quickly discovers that the town has a dark history of being haunted by a ghostly woman who drives residents to suicide.
A boy named Eli with a rare autoimmune disorder is confined to a special experimental clinic for his treatment. He soon begins experiencing supernatural forces, turning the supposedly safe facility into a haunted prison for him and his fellow patients.