Tom and Mae Garvey are a Tennessee farming couple battling violent floods to save their land. In addition to natural disasters, the Garveys fight to stop a selfish land developer and a local corporation from foreclosing on their farm. While Mae stays at home to care for their children and tend to the crops, Tom finds work as a scab at a steel mill to preserve his family's property.
Julie is a new mom and children's book author, who escapes into the bright Crayola-colored world of her creation in order to leave behind the darkness caused by her post-partum depression.
In a suburban landscape, the lives of several families interlace with loss, despair and personal crisis. Esther Gold has lost focus on all but caring for her comatose son, Paul, and neglects her daughter and husband. Lawyer Jim Train is devoted to his career, not his family. Helen Christianson wants to find a new spark in life, while Annette Jennings tries to rebuild hers.
Jack McKee is a doctor with it all: he's successful, he's rich, and he has no problems.... until he is diagnosed with throat cancer. Now that he has seen medicine, hospitals, and doctors from a patient's perspective, he realises that there is more to being a doctor than surgery and prescriptions.