Middle-aged family man Arnaldo is kicked out by his wife because of a misunderstanding. Instead of despairing, Arnaldo takes advantage of the situation to turn around his unsatisfying adult life by going to live in a flat shared with four university students.
A vicious serial sex killer is on the loose, and landscape gardener and shop-window outfitter Loris is the prime suspect, thanks to his unfortunate habit of getting caught in compromising situations (for which there is always a totally innocent explanation that the police fail to spot). Undercover policewoman Jessica is assigned by eccentric police psychologist Taccone to follow Loris.
Sergio Benvenuti is a shy seller of contracts for a Roman company of music, but because of his character he cannot find even a customer, so he asks for help from a fellow named Nadia.
Private detective Moses Wine is hired by his former college girlfriend to investigate a political smear campaign and he sets out to find out who is responsible, with deadly results.
Daryl Zero is a private investigator and—along with his assistant, Steve Arlo—he solves impossible crimes and puzzles. Although Daryl's a master investigator, he doesn't know what to do with himself when he's not working; he has no social skills, writes bad music and drives Steve crazy.