A young wife discovers that she has Hodgkin's Disease. It can be treated, but complicating the situation is the fact that she is pregnant, and the treatment can endanger the life of her unborn baby, as well as herself.
A showdown decades in the making brings the Donovan family legacy full circle. As the events that made Ray who he is today finally come to light, the Donovans find themselves drawn back to Boston to face the past. Each of them struggles to overcome their violent upbringing, but destiny dies hard, and only their fierce love for each other keeps them in the fight.
Two separate stories mesh - in the first, a young music teacher, Maggie Andrews, begins dying of a heart condition and her son Nathan tries to get a pair of Christmas shoes for her before she dies. In the second, lawyer Robert Layton and his wife Kate are slowly drifting apart and the matter comes to a head during Christmas when Kate takes over for Maggie for the school choir.
When Lori Reimuller learns that her young son Robbie has epilepsy, she first trusts the judgment of the hospital staff in how best to bring it under control. As Robbie's health slides radically downhill, however, she becomes frustrated and desperate, and so does her own research into the existing literature on treatments. When she decides to try an alternative treatment called the Ketogenic Diet, devised long ago by a doctor from Johns Hopkins, she is met with narrow-minded resistance from Robbie's doctor, who is prepared to take legal action to prevent Lori from removing him from the hospital.