Upon waking up to the news that the man she’d gone on a date with the previous night has been murdered, a young woman with only a faint memory of the night’s events begins to suspect that she murdered him while attempting to resist his advances.
In New York City, an insolent pickpocket, Skip McCoy, inadvertently sets off a chain of events when he targets ex-prostitute Candy and steals her wallet. Unaware that she has been making deliveries of highly classified information to the communists, Candy, who has been trailed by FBI agents for months in hopes of nabbing the spy ringleader, is sent by her ex-boyfriend, Joey, to find Skip and retrieve the valuable microfilm he now holds.
Arthur Bishop is a veteran hit man who, owing to his penchant for making his targets' deaths seem like accidents, thinks himself an artist. It's made him very rich, but as he hits middle age, he's so depressed and lonely that he takes on one of his victim's sons, Steve McKenna, as his apprentice. Arthur puts him through a rigorous training period and brings him on several hits. As Steven improves, Arthur worries that he'll discover who killed his father.
While attending a glamorous jazz cruise on New York’s East River, Nick and Nora Charles witness the fatal shooting of a wealthy patron. When suspicion falls on a young bandleader and his musicians, the couple steps in to clear their friends and uncover the real killer. Their investigation leads through a lively world of jazz clubs, radio personalities, high society, and backstage rivalries, where almost everyone has a secret and the next clue may be hidden in the music.