Two strangers are drawn to a mysterious pharmaceutical trial that will, they're assured, with no complications or side-effects whatsoever, solve all of their problems, permanently. Things do not go as planned.
A family of aliens from a much better world must take refuge in middle America after the destruction of their planet. Their mission: protect the Pupa, a living super computer that will one day evolve into its true form, consume them and terraform the Earth.
Everyone else sees Wilfred as just a dog, but Ryan sees a crude and somewhat surly, yet irrepressibly brave and honest Australian bloke in a cheap dog suit. While leading him through a series of comedic and existential adventures, Wilfred the dog shows Ryan the man how to overcome his fears and joyfully embrace the unpredictability and insanity of the world around him.
The story of the town and people who live above “The Loop,” a machine built to unlock and explore the mysteries of the universe – making things possible that were previously relegated only to science fiction.