Sana Dalawa ang Puso follows the story of Mona Bulalayao and Lisa Laureano (both played by Jodi Sta. Maria), two different women with identical faces; both facing challenging ordeals in their lives.
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The Diaz siblings, Lily and Jorge, are on a mission to find love and purpose. They cross paths with seemingly unrelated residents during some of the most heightened days of the year—the holidays.
The scandalous lives of Liz and Michael, a cop and a lawyer who meet in a near-fatal coincidence. Drama and comedy with inevitable and powerful chemistry between a man and woman that completely alter a destined life plan.
In the near future, Sophie tells her son the story of how she met his father: a story that catapults us back to the year 2021 where Sophie and her close-knit group of friends are in the midst of figuring out who they are, what they want out of life, and how to fall in love in the age of dating apps and limitless options.
When her boyfriend Derwin Davis is chosen as the new third-string wide receiver for the San Diego Sabers, Melanie Barnett decides to attend a local college so she can be with him. While Derwin worries about the plays on the field, Melanie adjusts to her new lifestyle. She gets a play-by-play account of the lives and relationships among NFL wives, girlfriends and mom/managers who use their best game to help their men stay on the field and on their arm.
In 1984, Maximo Gallardo's dream comes true when he gets the job of a lifetime at Acapulco's hottest resort, Las Colinas. But he soon realizes that working there will be far more complicated than he ever imagined.
After Neurosurgeon Maggie Sullivan’s personal and professional life are thrown into turmoil she returns home to Sullivan’s Crossing. While there, Maggie is forced to navigate her complicated present while confronting the painful past she has chosen to ignore for years.