The tragic and controversial story of Cameron Todd Willingham, who was executed in Texas for killing his three children after scientific evidence and expert testimony that bolstered his claims of innocence were suppressed.
Detective Chief Superintendent Maurice Jobson is forced to remember the very similar disappearance of Clare Kemplay, who was found dead in 1974, and the subsequent imprisonment of local boy Michael Myshkin. Washed-up local solicitor John Piggott becomes convinced of Myshkin's innocence and begins to fight on his behalf, unwittingly providing a catalyst for Jobson to start to right some wrongs.
Deputy Sheriff Lou Ford is a pillar of the community in his small west Texas town, patient and apparently thoughtful. Some people think he is a little slow and maybe boring, but that is the worst they say about him. But then nobody knows about what Lou calls his "sickness": He is a brilliant, but disturbed sociopathic sadist.
A psychotic man opens fire in a diner, murdering numerous people before killing himself. The survivors struggle in different ways following this horrendous event: a doctor doubts his own instincts and elects to use an experimental medical procedure on his wife, while a gambler believes he's on a lucky streak. A waitress begins engaging in promiscuous sex, and a young girl whose father is among the dead gains unexpected fame.
Struggling but unapologetically living on her own terms, Inez is moving from shelter to shelter in mid-1990s New York City. With her 6-year-old son Terry in foster care and unable to leave him again, she kidnaps him so they can build their life together. As the years go by, their family grows and Terry becomes a smart yet quiet teenager, but the secret that has defined their lives threatens to destroy the home they have so improbably built.
A newspaper publisher, wanting to prove a point about the insufficiency of circumstantial evidence, talks his possible son-in-law Tom into a hoax in an attempt to expose ineptitude of the city's hard-line district attorney. The plan is to have Tom plant clues leading to his arrest for killing a female nightclub dancer. Once Tom is found guilty, he is to reveal the setup and humiliate the DA.