In 1976 San Francisco, 15-year-old aspiring cartoonist Minnie begins keeping an audio diary. She is stirred by her awakening sexuality and wants to lose her virginity. She fears she may be unattractive, but receives attention from boys at school.
Womanising, right-wing Dan Hanson and quiet, liberal Lorie Bryer work for the Baltimore Sun. Rivals for the job of new writer of a vacant column, the paper ends up instead printing their very different opinions alongside each other, which leads to a similarly combative local TV show. At the same time their initial indifference to each other looks like it may evolve into something more romantic.
For Tobe, a nerdy, horny, frizzy-haired cineaste who doesn't quite fit in with the average contemporary teen, the pinnacle of womanhood is Monica Velour, a soft-core actress who reached the zenith of her career in the 1980s. When Tobe learns that his love idol is headlining hundreds of miles away at the Gentlemen's Petting Zoo in Indiana, he drives off with carefree glory, filled with the hope of meeting her.
A free-spirited young woman, Breezy, hitches a ride with an aging real estate salesman, Frank. Sensing that she just wants to use him he tries to have nothing to do with her. She's not that easy to shake, however, and over time a bond forms between them.
When her all-male house-cleaning business gets out of control, a mature woman must embrace her own sexuality, if she is to make a new life for herself.
Lucy and Jane have been best friends for most of their lives and think they know everything there is to know about each other. But when Jane announces she's moving to London, Lucy reveals a long-held secret. As Jane tries to help Lucy, their friendship is thrown into chaos.