The film contains five stories set on desolate stretches of a desert highway. Two men on the run from their past, a band on its way to a gig, a man struggling to get home, a brother in search of his long-lost sister and a family on vacation are forced to confront their worst fears and darkest secrets in these interwoven tales.
As an evil takes over the world beyond their front doorstep, the only protection for a mother and her twin sons is their house and their family’s protective bond.
Five train passengers are joined by a mysterious fortuneteller who offers to read Tarot. A quintet of stories unfold: an architect returns to his ancestral home to find a vengeful werewolf; a doctor suspects his new wife is a vampire; an intelligent vine takes over a house; a jazz musician plagiarises music from a voodoo ceremony; and a pompous art critic is pursued by a disembodied hand.
A series of down-on-their-luck individuals enter the decrepit and spine-chilling Rialto theater, only to have their deepest and darkest fears brought to life on the silver screen by The Projectionist – a mysterious, ghostly figure who holds the nightmarish futures of all who attend his screenings.
A horror anthology containing three stories: a female college professor is aggressively pursued by one of her students; a prudish brunette determines that her free-spirited blonde sister is evil; and a woman's night turns upside down after she purchases an ancient Zuni fetish doll.