Reclusive vampires lounge in a lonely American town. They wear sunscreen to protect themselves. A descendant of Van Helsing arrives with hilarious consequences.
Mark wants to lose his virginity, but his girlfriend wants to wait. Unfortunately for both of them, a 400-year-old vampire Countess needs to turn a virgin into a vampire before Halloween in order to preserve her own youthful appearance, and when she finds Mark, she turns his life upside-down.
Charley Brewster, a high school student, accidentally discovers the true and creepy nature of Jerry Dandrige, his dashing and enigmatic new neighbor; but no one seems willing to believe him.
Anthropologist Joe Weber takes his son on a trip to the New England town of Salem's Lot, unaware of its vampire population. When the inhabitants reveal their secret, they seek Weber to write a bible for them.
When his home of New Eden is destroyed by a revitalized Brotherhood and its new Vamp leader, Martin finds himself alone in the badlands of America with only the distant memory of his mentor and legendary vampire hunter, Mister, to guide him.