Humanity must resume its war against the Martians when they revive after decades of hibernation following their defeat in the 1950s. The fate of Earth may very well rest in the hands of a small yet courageous band: astrophysicist Harrison Blackwood, paraplegic computer wizard Norton Drake, microbiologist Suzanne McCullough and military man Paul Ironhorse.
Wyatt Earp's great granddaughter Wynonna battles demons and other creatures with her unique abilities and a posse of dysfunctional allies - the only thing that can bring the paranormal to justice.
In this new era, Catalina, now head of the DEA in Colombia, has a new challenge: to track down a criminal organization that is trafficking a new synthetic drug. What she ignores is that her daughter is part of the Cartel that traffics them and that Yésica, her worst enemy, is infiltrated in the DEA.