Detective Hollis Lucetti (Terrence Howard) receives news from a doctor that he has been Sterility (physiology) his entire life. Upon reaching home, he questions his wife about who their children's father is.
On a steamy New Orleans afternoon, Sam Deuprey decides to surprise his beautiful wife, Ashley, for their anniversary and comes home early. But Ashley is not alone in the bedroom. She and her lover, Damien are about to learn how far a jealous husband will go.
Ava, a young bank professional is devastated when her husband Dallas abandons a marriage she is determined to fight for until fate intervenes, revealing Dallas' wicked deeds that have trashed their marriage, and once upon a time sabotaged Ava's destiny to be loved by her true soulmate.
A nightmarish evening unfolds for neighbors David and Robert when they accidentally hit a woman on her bike and flee the scene. While David is increasingly plagued by feelings of guilt, Robert shows no remorse and becomes overbearing and possessive.