Charlie Cale has the extraordinary ability to determine when someone is lying. She hits the road with her Plymouth Barracuda and with every stop encounters a new cast of characters and strange crimes she can’t help but solve.
Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.
Family Liaison Officer Lisa Armstrong becomes a little too emotionally involved with a case (to the point where she might compromise it) concerning a pair of missing Morecambe twins to whose distraught parents she is assigned.
DCI Ellis, a tenacious cop, is parachuted into failing investigations alongside her partner DS Harper. Each case will bring her to a different police station where she'll have to not only immerse herself in the case, but also win over the local police.
How do you solve a murder in a post-fact world? Especially when sailing the Mediterranean on an ocean liner filled with the wealthy and powerful. Everyone on board is hiding something… but is one of them a killer? That’s what the world’s once greatest detective, Rufus Cotesworth, and his protégée, Imogene, aim to discover.