Typical of Arriaga's works, this film is told in a nonlinear narrative, where events are revealed out of sequence. The following plot summary is in chronological order, thus does not reflect the exact sequence of the events as seen on screen.
Waitress Annie has separated from her suicidal alcoholic husband, Glenn. Glenn has become an evangelical Christian, but his erratic attempts at getting back into Annie's life have alarmed her. High school student Arthur works at Annie's restaurant, growing closer to a new kid in town, Lila, after class. When Glenn and Annie's daughter goes missing, the whole town searches for her, as he increasingly spirals out of control.
18-year-old Noah moves from America to London, with her mother who's recently fallen in love with William, a wealthy British businessman. Noah meets William’s son, bad-boy Nick, and soon discovers there is an attraction between them neither can avoid. As Noah spends the summer adjusting to her new life, her devastating past will catch up with her while falling in love for the first time.
In 19th-century France, doctor's wife Emma Bovary seeks to escape her dull provincial life through various extramarital affairs and extravagant spending, leading to tragic consequences.
Max Baron is a Jewish advertising executive in his 20s who's still getting over the death of his wife. Nora Baker is a 40-something diner waitress who enjoys the wilder side of life. Mismatched or not, their attraction is instant and smoldering. With time, however, their class and age differences become an obstacle in their relationship, especially since Max can't keep Nora a secret from his Jewish friends and upper-crust associates forever.