When lapsed Jew and former cardiologist Harry suddenly decides to spend his retirement as a pig farmer in Nazareth, Israel, the move deeply shocks his family and his new neighbours. Back in New York, Harry’s ex-wife Monica is trying to manage the lives of their adult children, Annabelle and David, as well as her own.
Jo, the mother of seven children, divorces her second husband in order to marry Jake, a successful but promiscuous screenwriter. Though they are physically and emotionally compatible, they are slowly torn apart.
Tempted away from Newcastle United to join Real Madrid, rising star Santiago Munez finds this latest change of fortune the greatest challenge yet - personally as well as professionally. He is reunited with Gavin Harris, though they must compete to be on the team, and estranged from fiancee Roz, whose nursing career keeps her back home.
94-year-old Eleanor Morgenstein tries to rebuild her life after the death of her best friend. As a result, she moves back to New York City after living in Florida for decades.