A quiet, stoic man, lives a monk-like existence in self-imposed exile. When his estranged son is killed in a drug deal gone bad, he is left to look after a granddaughter he never knew existed, and he is forced back into a life he tried to put behind him.
Over the course of one night, a woman drives across LA with her heroin addict brother in search of a detox center, with his two-year-old daughter in tow.
Jack Caine is a Houston vice cop who's forgotten the rule book. His self-appointed mission is to stop the drugs trade and the number one supplier Victor Manning. While involved in an undercover operation to entrap Victor Manning, his partner is killed, and a sinister newcomer enters the scene...
A stark portrayal of life among a group of heroin addicts who hang out in Needle Park in New York City. Played against this setting is a low-key love story between Bobby, a young addict and small-time hustler, and Helen, a homeless girl who finds in her relationship with Bobby the stability she craves.
A young heroin addict roams the streets of New York to panhandle and get her next fix, while her unstable boyfriend drifts in and out of her life at random.