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Dr. Bock, the chief of medicine at a Manhattan hospital, is suicidal after the collapse of his personal life. When an intern is found dead in a hospital bed, it appears to Bock to be a case of unforgivable malpractice. Hours later, another doctor, who happens to be responsible for another case of malpractice, is found dead. Despondent, Bock finds himself drawn to Barbara, the daughter of a comatose missionary.
When his daughter is murdered, William Duncan takes the law into his own hands, setting out on a quest for retribution. After killing the street thug responsible for her death, he finds himself in the middle of a war with the thug's brother, father, and their gang, who are equally hell-bent on getting even. What ensues is a tense back-and-forth game of vengeance. By the end, William comes to find that the quest for revenge never has a winner.
In an attempt to avenge her daughter’s death, Irene Kelly travels through parallel universes, killing her daughter’s murderer again and again. As she becomes consumed by vengeance, her humanity begins to slip away—until the cycle is disrupted when she rescues Mia, a sharp-witted teenager already marked by the killer.
Anna returns home after spending time in a psychiatric facility following her mother's tragic death and discovers that her mother's former nurse, Rachel, has moved into their house and become engaged to her father. Soon after she learns this shocking news, Anna is visited by her mother's ghost, who warns her that Rachel has evil intentions.
A brilliant but deranged neurosurgeon becomes obsessively fixated on a judge's daughter. With the help of an escaped criminal whose face he has surgically deformed, the mad man lures her, her father, and her fiancé to his isolated, castle-like home.
A twice-divorced mother of three who sees an injustice, takes on the bad guy and wins -- with a little help from her push-up bra. Erin goes to work for an attorney and comes across medical records describing illnesses clustered in one nearby town. She starts investigating and soon exposes a monumental cover-up.