Demetrio Azunsolo arrives in a small remote village outside Mexico where his beloved half-brother, Ricardo Platas, used to live and run a tequila plantation, only to find out that the latter has just committed suicide, after being betrayed by a selfish, greedy woman.
Manuel's life is upended when Esmeralda, his lost love from 15 years ago, calls unexpectedly. Despite being set to marry another, he rediscovers Esmeralda, and they realize their love transcends time.
Ana and her two best friends, Maria and Paula, navigate life in their oppressive countryside village. Whilst their families struggle in the poppy fields harvesting opium, the girls try to grow alongside the creeping terror of their cartel oppressors.