May 1940, a mother is on the run with her two little girls. Due to a lack of gasoline she can't go far and harbours her children near a Lourdes grotto.
A poor, struggling South Carolinian mother and daughter face painful choices with their resolve and pride. Bone, the eldest daughter, and Anney her tired mother, grow both closer and farther apart: Anney sees Glen as her last chance.
Middle-aged widow Beatrice Hunsdorfer and her daughters Ruth and Matilda are struggling to survive in a society they barely understand. Beatrice dreams of opening an elegant tea room but does not have the wherewithal to achieve her lofty goal. Epileptic Ruth is a rebellious adolescent, while shy but highly intelligent and idealistic Matilda seeks solace in her pets and school projects, including one designed to show how small amounts of radium affect marigolds.
American retired Judge Randall Nemes and his hired gun, Gaspar, track down a con man posing as a priest in a small Colombian town only to be thrown off-course by a scrappy 16-year-old girl intent on reuniting with her sister in the United States.