In a suburban landscape, the lives of several families interlace with loss, despair and personal crisis. Esther Gold has lost focus on all but caring for her comatose son, Paul, and neglects her daughter and husband. Lawyer Jim Train is devoted to his career, not his family. Helen Christianson wants to find a new spark in life, while Annette Jennings tries to rebuild hers.
Middle-aged widow Beatrice Hunsdorfer and her daughters Ruth and Matilda are struggling to survive in a society they barely understand. Beatrice dreams of opening an elegant tea room but does not have the wherewithal to achieve her lofty goal. Epileptic Ruth is a rebellious adolescent, while shy but highly intelligent and idealistic Matilda seeks solace in her pets and school projects, including one designed to show how small amounts of radium affect marigolds.
A poor, struggling South Carolinian mother and daughter face painful choices with their resolve and pride. Bone, the eldest daughter, and Anney her tired mother, grow both closer and farther apart: Anney sees Glen as her last chance.
Released from jail, Lang returns to his hometown in Northwest China. As part of a dog patrol tasked with clearing stray dogs before the 2008 Olympics, he bonds with a black stray. The two lonely souls embark on a new journey together.