A chemical engineer, who recently moved to town, struggles to find a way to kill a deadly new variant of Cryptosporidium that has infiltrated the town's water supply, causing people who drink it to die of thirst.
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An emotionally unavailable flight attendant meets a potential love interest and later finds out that her "perfect guy" has ulterior motives. As the clock ticks down on New Year's Eve, she must fight to keep her murdered ex-boyfriend's secrets or find herself dead.
Despite scientist Nathan's warnings, his boss continues an experiment meant as publicity for his satellite firm: exploding an asteroid. Instead it splits, and the major piece, the size of Iceland, changes course to earth. It is deflected but so close that it shift our course closer to the sun, causing rapid extreme heating, hopefully only mid-term. Nathan warns his sister, TV journalist Carly, and she her lover, police detective Tom. He brings his unruly daughter Kim, her ex-con lover C.J. and her mother, nurse Bonnie, when Nathan offers a flight to a friend's Arctic weather station. Tom takes charge of a dangerous trip to the airport, as everywhere on earth things catch fire and people fight for water, transport and sheer looting.
When an unexpected road rage incident puts his son in critical condition, an enraged father spirals down a dark path of emotional turmoil and vengeance.
The Sheffield family reveal and go through some home truths as their middle child inherits the Foxworth mansion. The family's ghosts looming over, and more tragedies are in store as the curse lives on.
Thomas Montgomery, a married father of two young daughters, gets seduced by the world of online gambling and chat rooms where a virtual romance and sexual obsession ultimately leads to the murder of an innocent man.
Christopher and Cathy Dollanganger live together as man and wife with Cathy's two sons who are unaware of the incestuous nature of their parents' relationship. But when a mysterious woman moves in next door and befriends the younger boy, Bart, he begins a strange transformation and displays accusatory behavior towards Cathy and Christopher. When Christopher discovers their mysterious neighbor is, in fact, his mother Corrine Dollanganger, all of the family's long-hidden secrets are revealed in a tragic climax.