After struggling and finally conceiving a child, Roxy and Vinnie Ventola, a successful television writing couple, learns that their newborn has AIDS. Soon afterward, the two parents are also diagnosed with the fatal virus.
John, a 35-year-old window cleaner, has dedicated his life to bringing up his 4-year-old son, Michael, after the child's mother left them soon after giving birth. When John is given only a few months left to live, he attempts to find a new, perfect family for Michael, determined to shield him from the terrible reality of the situation.
Teenagers Rose and Bennett were in love, and then a car crash claimed Bennett's life. He left behind a grieving mother, father and younger brother, and Rose was left all alone. She has no family to turn to for support, so when she finds out she's pregnant, she winds up at the Brewer's door. She needs their help, and although they can't quite admit it, they each need her so they can begin to heal.