It's just another day in the small town of Hamlin until something disastrous happens. Suddenly, news breaks that a series of nuclear warheads has been dropped along the Eastern Seaboard and, more locally, in California. As people begin coping with the devastating aftermath of the attacks — many suffer radiation poisoning — the Wetherly family tries to survive.
Jamie Graham, a privileged English boy, is living in Shanghai when the Japanese invade and force all foreigners into prison camps. Jamie is captured with an American sailor, who looks out for him while they are in the camp together. Even though he is separated from his parents and in a hostile environment, Jamie maintains his dignity and youthful spirit, providing a beacon of hope for the others held captive with him.
In 1950s Pittsburgh, a frustrated African-American father struggles with the constraints of poverty, racism, and his own inner demons as he tries to raise a family.
When his family moves from their home in Berlin to a strange new house in Poland, young Bruno befriends Shmuel, a boy who lives on the other side of the fence where everyone seems to be wearing striped pajamas. Unaware of Shmuel's fate as a Jewish prisoner or the role his own Nazi father plays in his imprisonment, Bruno embarks on a dangerous journey inside the camp's walls.