During an ever-growing epidemic of zombies that have risen from the dead, two Philadelphia SWAT team members, a traffic reporter, and his television-executive girlfriend seek refuge in a secluded shopping mall.
Retired military commander Colonel Dale Murphy hosts the simulated post-apocalyptic reality show where participants are challenged to survive a remote West Virginia wasteland. But the show turns into a nightmarish showdown when each realizes they are being hunted by an inbred family of cannibals determined to make them all dinner!
High-tech robots equipped with state-of-the-art security devices have been recruited as the new mechanical "night watchmen" for the Park Plaza Mall. When a jolting bolt of lightning short-circuits the main computer control, the robots turn into "killbots" on the loose after unsuspecting shoppers!
Two doctors find their graveyard shift inundated with townspeople ravaged by sores. Among the wounded is Cherry Darling, a dancer whose leg was ripped from her body. As the invalids quickly become enraged aggressors, Cherry and her ex-boyfriend El Wray lead a team of accidental warriors into the night.
When his home of New Eden is destroyed by a revitalized Brotherhood and its new Vamp leader, Martin finds himself alone in the badlands of America with only the distant memory of his mentor and legendary vampire hunter, Mister, to guide him.