In response to a global rise in demonic possessions, the Catholic Church reopens exorcism schools to train priests in the Rite of Exorcism. On this spiritual battlefield, an unlikely warrior rises: a young nun, Sister Ann. Thrust onto the spiritual frontline with fellow student Father Dante, Sister Ann finds herself in a battle for the soul of a young girl and soon realizes the Devil has her right where he wants her.
An orphaned girl is rescued from a satanic ritual and taken to Saint Catherine Institute for homeless youth. There she will learn new skills while facing demons that stalk her.
Ebony Jackson, a struggling single mother fighting her personal demons, moves her family into a new home for a fresh start. But when strange occurrences inside the home raise the suspicions of Child Protective Services and threaten to tear the family apart, Ebony soon finds herself locked in a battle for her life and the souls of her children.
On the fifteenth anniversary of the exorcism that claimed Father Damien Karras' life, Police Lieutenant Kinderman's world is once again shattered when a boy is found decapitated and savagely crucified.