Dan Hammond returns to Texas after the war, as does brother Neil, who simply wants to run a small ranch. Dan's ambition is to build an empire the way ruthless Cord Hardin has.
In the turn-of-the century Texas town of Cottonwood Springs, marshal Frank Patch is an old-style lawman in a town determined to become modern. When he kills drunken Luke Mills in self-defense, the town leaders decide it's time for a change. That ask for Patch's resignation, but he refuses on the basis that the town, on hiring him, had promised him the job for as long as he wanted it. Afraid for the town's future and even more afraid of the fact that Marshal Patch knows all the town's dark secrets, the city fathers decide that old-style violence is the only way to rid themselves of the unwanted lawman.
Dan Ballard, a respected citizen in the western town of Silver Lode, has his wedding interrupted by four men led by Ned McCarty, an old acquaintance who, as a US Marshal, arrests Ballard for the murder of his brother and the theft of $20,000. Ballard seeks to stall McCarty while tracking down evidence that will prove his innocence.
Texas Ranger Jake Cutter arrests gambler Paul Regret, but soon finds himself teamed with his prisoner in an undercover effort to defeat a band of renegade arms merchants and thieves known as Comancheros.
In early 20th-century Montana, Col. William Ludlow lives on a ranch in the wilderness with his sons, Alfred, Tristan, and Samuel. Eventually, the unconventional but close-knit family are bound by loyalty, tested by war, and torn apart by love, as told over the course of several decades in this epic saga.
After the Civil War, Confederate soldiers Clint and Vance Reno steal a Union payroll, leading to conflict when the younger marries the woman his older brother loves.