It's in the early 18th century. The priest Martin Ryselius has become widower and stands alone with a one-year-old daughter. He is seeking the meaning of existence by heading north in Sweden for a priesthood service in the mountains.
Middle-aged widow Beatrice Hunsdorfer and her daughters Ruth and Matilda are struggling to survive in a society they barely understand. Beatrice dreams of opening an elegant tea room but does not have the wherewithal to achieve her lofty goal. Epileptic Ruth is a rebellious adolescent, while shy but highly intelligent and idealistic Matilda seeks solace in her pets and school projects, including one designed to show how small amounts of radium affect marigolds.
A young priest, Father Chisholm is sent to China to establish a Catholic parish among the non-Christian Chinese. While his boyhood friend, also a priest, flourishes in his calling as a priest in a more Christian area of the world, Father Chisholm struggles. He encounters hostility, isolation, disease, poverty and a variety of set backs which humble him, but make him more determined than ever to succeed.
American retired Judge Randall Nemes and his hired gun, Gaspar, track down a con man posing as a priest in a small Colombian town only to be thrown off-course by a scrappy 16-year-old girl intent on reuniting with her sister in the United States.
A poor, struggling South Carolinian mother and daughter face painful choices with their resolve and pride. Bone, the eldest daughter, and Anney her tired mother, grow both closer and farther apart: Anney sees Glen as her last chance.