Stan and Ollie are mousetrap salesmen hoping for better business in Switzerland, with Stan's theory that because there is more cheese in Switzerland, there should be more mice.
A pampered dog named Trouble must learn to live in the real world while trying to escape from his former owner's greedy children and must learn how to survive on the big-city streets.
The Newton family live in their comfortable home, but there seems to something missing. This "hole" is filled by a small puppy, who walks into their home and their lives. Beethoven, as he is named, grows into a giant of a dog... a St Bernard. Doctor Varnick, the local vet has a secret and horrible sideline, which requires lots of dogs for experiments. Beethoven is on the bad doctor's list.
When a radio falls from the sky into the hands of a wide-eyed Tibetan Mastiff, he leaves home to fulfill his dream of becoming a musician, setting into motion a series of completely unexpected events.
Best friends Tod, a fox kit, and Copper, a hound puppy, visit a country fair when they see a band of dogs called "The Singin' Strays". The band has five members: Dixie, Cash, Granny Rose, and twin brothers Waylon and Floyd. It is important that they perform well because a talent scout is visiting.