30-year-old single Mary Richards moves to Minneapolis to start a new life after a romantic break-up. There she reacquaints with Phyllis who rents her a room, and meets her upstairs neighbor and new best friend Rhoda. Mary unexpectedly lands a job as associate producer at the TV station WJM, where she works alongside her bristly boss, Lou; the comical newswriter, Murray; and the newscast's often-incompetent anchor, Ted.
Liz Lemon kaotik bir skeç programını, tuhaf ekibini ve otoriter patronunu idare ederken felaketlerle dolu özel hayatını toparlamaya ve geceleri peynir yemeye çalışır.
Claude Casey moved up in the secretarial world of television news, from temp to the anchor's desk. After her boss hires her full time, Claude realizes she may be in over her head in this world of assistants fighting to get ahead. But Claude is determined to prove that though she may not be perfect, she's not going down without a fight.
When a Cincinnati radio station switches from sedate music to top-40 rock 'n' roll, its staff of oddball characters is forced to switch gears quickly. New programming director Andy Travis brings in a new DJ named Venus Flytrap to work with the station's burned-out veteran, Dr. Johnny Fever. Neurotic newsman Les Nessman, eager beaver Bailey Quarters, sleazy salesman Herb Tarlek, blonde bombshell Jennifer Marlowe, who serves as the station's ultra-capable receptionist, and station manager Arthur Carlson, whose domineering mother owns WKRP, round out the eccentric bunch.