A psychiatric hospital is turned upside down when a mysterious drifter is admitted and assigned to room 316. Known only as John Doe, the other patients believe that he bears an uncanny resemblance to Jesus Christ.
Russ Millings has just been released from prison after serving 21 years for a 3rd strike conviction for possessing an ounce of marijuana. As he tries to adapt to a world he doesn’t recognize – including trying to learn how to use the internet – he finds an abandoned baby in a dumpster behind the fast food restaurant where he works as a dishwasher. Unsure of what to do, and caught between impulses of kindness and panic, Russ soon realizes this could be his chance at redemption.
Middle-aged widow Beatrice Hunsdorfer and her daughters Ruth and Matilda are struggling to survive in a society they barely understand. Beatrice dreams of opening an elegant tea room but does not have the wherewithal to achieve her lofty goal. Epileptic Ruth is a rebellious adolescent, while shy but highly intelligent and idealistic Matilda seeks solace in her pets and school projects, including one designed to show how small amounts of radium affect marigolds.
A psychotic man opens fire in a diner, murdering numerous people before killing himself. The survivors struggle in different ways following this horrendous event: a doctor doubts his own instincts and elects to use an experimental medical procedure on his wife, while a gambler believes he's on a lucky streak. A waitress begins engaging in promiscuous sex, and a young girl whose father is among the dead gains unexpected fame.
Up-and-coming sports reporter rescues a homeless man ("Champ") only to discover that he is, in fact, a boxing legend believed to have passed away. What begins as an opportunity to resurrect Champ's story and escape the shadow of his father's success becomes a personal journey as the ambitious reporter reexamines his own life and his relationship with his family.