Upon arriving at the Digital World after the "reboot", the digidestined are hunted by a new villain. Meanwhile, Sora is troubled by her partner digimon's indifference towards her.
Meicoomon rampages after witnessing Meiko Mochizuki being injured by the man bearing Gennai's likeness. "It would have been better if you hadn't been born..." Meicoomon disappears into the Real World, which has since become distorted. Possessing overwhelming power, she's the key to the world's destruction.
In 2012, after the events of Digimon Adventure: Last Evolution Kizuna, the early adulthood DigiDestined—Daisuke, Miyako, Iori, Takeru Takashi, Hikari, and Ken—must reconcile their new responsibilities with their Digimon partners. But Rui Owada, a mysterious young man, appears, claiming to be the first human to partner with a Digimon–Ukkomon. Could Rui really have been the first-ever DigiDestined?
The DigiDestined go to a nearby hot springs theme park and everyone has a good time, but Joe doesn't show up because he wants to study for his exams. Another infected Digimon, Ogremon, attacks Odaiba. Gomamon runs away from home while Mimi faces problems with the other DigiDestined and her classmates because of her selfish ideas.
Tai is now a university student, living alone, working hard at school, and working every day, but with his future still undecided. Meanwhile, Matt and others continue to work on Digimon incidents and activities that help people with their partner Digimon. When an unprecedented phenomenon occurs, the DigiDestined discover that when they grow up, their relationship with their partner Digimon will come closer to an end.
The battle is over, and they can go about their normal lives now... or so they thought. With no time to rejoice after miraculously saving Mirai from Beyond the Boundary, Mirai lost all her memories. Akihito, now a high school senior, starts to avoid Mirai thinking it’s for the better. Not aware of Akihito’s feelings, Mirai tries to get closer to Akihito. Then, someone who knows of Mirai appears in front of the two. With Akihito’s troubles in vain, Mirai once again sets forth on a battle that forces her to look within.