The anime follows a salaryman who has a chance meeting with a girl named Ai on the train. They begin to meet every Monday on the train, with the man serving as her bodyguard on the crowded commute while they chat.
Godai is a ronin (someone who has failed university entrance exams) living in a run down apartment house called Maison Ikkoku. Among the other residents are the nosy Ichinose, the sexy Akemi Roppongi, and the mysterious Yotsuya. The others are given to having wild parties which makes it difficult for Godai to study. Into this mayhem comes the recently widowed Kyoko as the new live-in manager. Godai falls for her, but doesn't have the nerve to tell her. As time passes, their relationship slowly develops amid life at Maison Ikkoku, despite all sorts of romantic hurdles.
Being an adult is hard, and for Uramichi Omota, that truth weighs on him. While on TV, he’s the upbeat exercise instructor for a children’s show, but he and his coworkers keep revealing the plight of adulthood on air. At least they’re working through it.
Sasahara Kanji is a college freshman who decides to join a student society to share his hidden thoughts on manga, anime and gaming. As he participates in club activities such as visiting dojin shops and anime festivals he opens his mind and resolves that he will make his way into the otaku world.
The story follows Rena Yukuhasahi, a reserved office lady and Ryouhei Hachiya, a businessman and fellow colleague. Yukuhasahi appears to be the most reserved girl in the company, but becomes a super beautiful woman when she dresses up. Flustered in the presence of her transformed self, Hachiya insists on taking her out, only to find themselves in front of a love hotel.
Miyako is a shy college student who is also an otaku. One day she happens to meet some angelic grade school kids! When Miyako sees her little sister's new friend Hana-chan, Miyako's heart won't stop racing! Miyako tries to get along with them but struggles... A sketch comedy all about trying to get along with the super cute girl is about to begin!