FBI'ın uluslararası departmanındaki seçkin ajanlarının, dünyanın dört bir yanındaki Amerikalıları korumak için yaptıkları nefes kesici operasyonları konu alıyor.
Vinnie Terranova does time in a New Jersey penitentiary to set up his undercover role as an agent for the OCB (Organized Crime Bureau) of the United States. His roots in a traditional Italian city neighborhood form the underlying dramatic base throughout the series, bringing him into conflict with his conservative mother and other family members while acting undercover as syndicate enforcer.
The FBI's team of Cyber Crime Investigators, headed by Special Agent Avery Ryan, works to solve cases involving the dark-net. Avery, a Special Agent in Charge and esteemed Cyber-Psychologist heads up a team, including Senior Special Agent Elijah Mundo, tasked with solving murders, cyber-theft, hacking, sex offences, and blackmail.
Unorthodox but effective FBI veteran agent Charles Barker takes on a rookie partner, Ellis Dove. Barker trains Dove in a hard-edged, psychologically driven approach towards undercover work, where a moment's hesitation can lead to death. As the job takes its toll on Dove, an Internal Affairs team tries to enlist the rookie as a double-agent in the bureau's investigation of his partner.
Framed for murder, Detective Reno Raines becomes a fugitive bounty hunter who fights crime while trying to clear his name. His troubles began after he testified about police corruption, leading Lt. Donald Dixon to set him up.