Hitomi, Rui ve Ai hırsız kız kardeşlerdir. Üçüncü Lüpen'in Tokyo'ya geldiği dönemde müzeden bir tablo çalarlar. İki tablo da Michael Heinz'ın "Kız Çocuk ve Çiçekler" serisine aittir. Kedi kız kardeşler için tabloların önemi kayıp babaları Michael Heinz'ı bulmaları için değerli birer ipucudur. Efsanevi hırsızın da aynı hedeflerin peşinde olduğunu öğrendiklerinde içlerinde bir ateş yanar.
Foiled repeatedly by the predictions of Interpol's supercomputer, Lupin has settled down. His partner Jigen asks him to pull one last heist: recover the Super Egg, a massive diamond hidden somewhere inside the Statue of Liberty.
The infamous bandit Harimao hid a treasure, and to retrieve it, Lupin and the gang must gather three lost statues. When the Nazi-like group Neo-Himmel make a run for the goods, Lupin reluctantly partners with the aging "double-O" MI-6 agent Sir Archer and his granddaughter Diana to gather the statues first. Can this unorthodox team bond well enough to see this mission through?
Lupin steals an extraordinary gem from a Mediterranean party, only to be interrupted by Pycal, the trickster "magician" who had apparently died fighting Lupin early in his career. Pycal, now armed with real magical abilities, is determined to take revenge.
Lupin & Jigen have their sights set on a treasure called the Little Comet, which is located in the heavily fortified country of East Doroa. During the heist, Jigen is almost killed by a sniper named Yael Okuzaki. His specialty is preparing tombstones for his targets before executing them. It's said that no one can survive after Yael makes their tombstone.