A nun, the only survivor of an Indian massacre of a wagon train, is taken in by a cantankerous old gunfighter who helps her to evade the marauding Indians during her attempt to reach Sante Fe.
Jesse W. Haywood (Don Knotts) graduates from dental school in Philadelphia in 1870 and goes west to become a frontier dentist. Penelope "Bad Penny" Cushing (Barbara Rhoades) is offered a pardon if she will track down a ring of gun smugglers. She tricks Haywood into a sham marriage as a disguise. Haywood inadvertently becomes the legendary "Doc the Haywood" after he guns down "Arnold the Kid".
An authoritarian rancher rules an Arizona county with her private posse of hired guns. When a new Marshal arrives to set things straight, the cattle queen finds herself falling for the avowedly non-violent lawman. Both have itchy-fingered brothers, a female gunman enters the picture, and things go desperately wrong.
Notorious shootist and womanizer Quirt Evans' horse collapses as he passes a Quaker family's home. Quirt has been wounded, and the kindly family takes him in to nurse him back to health against the advice of others. The handsome Evans quickly attracts the affections of their beautiful daughter, Penelope. He develops an affection for the family and their faith, but his troubled past follows him.
Keskin nişancı serseri Dempsey Rae, güzel çiftçi Reed Bowman için çalışmak üzere Wyoming'e geri döner. Ancak Reed'in arazisinin geniş açık alanlarını çitle çevirme planı diğer çiftçileri kızdırır ve kısa süre sonra Dempsey'i kanlı bir menzil savaşına sürükler