Margherita, kariyerinin en önemli işi olarak gördüğü bir işçi filmi üzerinde geceli gündüzlü çalışmaktadır. Sette mükemmelliyetçi bir yönemen olarak çalışan Margherita her şeyin dört dörtlük olması için elinden gelen çabayı gösterirken, bir yandan da özel hayatındaki problemlerle mücadele eder. Annesi ciddi bir rahatsızlıktan muzdariptir ve ergenlik dönemindeki kızı beklenmedik çıkışlar yapmaktadır. Tüm bunların ortasında film setine gelen ABD'li oyuncu Barry Huggins, Margherita'nın filmini iyice çıkmaza sokacaktır...
Carlo and Elisa are a successful couple. He’s a university professor and writer facing a creative block; she’s a brilliant, sharp-witted journalist, known for her internationally published editorials. They live in Rome, moving between accomplishments and routine, affection and something that might be fading. In search of new energy, they travel to Morocco with their lifelong friends, Anna and Paolo, and their thirteen-year-old daughter Vittoria—bright, curious, a little eccentric. Tensions soon rise.
A middle-aged man, Pietro, becomes a widower and must take care of his daughter. He will never have the time to delve into his own pain, committing himself to raising his daughter with love and dedication, in an all-encompassing relationship in which one heals the other's wounds through his own. When, after a few years, he tries to start a new life with a new partner, not everything will go as hoped: his daughter's reaction will be exaggerated and Pietro will be put to the test. He will find himself struggling between anger and paternal instinct.
Young Father Giulio returns to Rome, where he was born and raised, to replace a priest who has left the clergy to start a family. He is delighted to reunite with his loved ones, especially his mother, sister, and old friends. Once radical leftists like Giulio himself, the latter are now each coping in their own way with the defeat of the revolution. Soon, however, Giulio realizes that despite his best efforts, he seems unable to solve the problems troubling those around him.
Felice returns to his native Rione Sanità in Naples to look after his dying mother, having lived abroad for the last forty years. Here he discovers that his old friend Oreste has become a notorious crimeboss.