Mrs. Nancy Gibson (Mary Astor) sets out to regain the affections of her cheating husband Donald Gibson (Robert Ames (actor)), after she returns from a trip to Paris (France), where she had to look after her sick mother.
A suburban architect loves his wife but is bored with his marriage and with his work, so he takes up with the neglected, married beauty who lives down the street.
A drunken newspaperman, Jerry Corbett, is rescued from his alcoholic haze by an heiress, Joan Prentice, whose love sobers him up and encourages him to write a play, but he lapses back into dipsomania.
A man and woman meet by chance at a romantic inn over dinner and, although both are happily married to others, they find themselves in the same bed the next morning questioning how this could have happened. They agree to meet on the same weekend each year—in the same hotel room—and the years pass each has some personal crisis that the other helps them through, often without both of them understanding what is going on.
One Rolls-Royce belongs to three vastly different owners, starting with Lord Charles, who buys the car for his wife as an anniversary present. The next owner is Paolo Maltese, a mafioso who purchases the car during a trip to Italy and leaves it with his girlfriend while he returns to Chicago. Finally, the car is owned by American widow Gerda, who joins the Yugoslavian resistance against the invading Nazis.